original idiotype - significado y definición. Qué es original idiotype
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Qué (quién) es original idiotype - definición

Immunoglobulin idiotypes; Immunoglobulin idiotype

idiotype         
['?d??(?)t??p]
¦ noun
1. Biology the set of genetic determinants of an individual.
2. Physiology a set of antigen-binding sites which characterizes the antibodies produced by a clone of cells.
YouTube Original Channel Initiative         
PROGRAM BY GOOGLE TO BRING CONTENT TO YOUTUBE
YouTube Original Channels Initiative; YouTube Original Channels
The YouTube Original Channel Initiative was a $100 million program funded by Google to bring original content onto Google. The original channel initiative was also meant to kick start Google TV.
Hair: Original Soundtrack Recording         
1979 SOUNDTRACK ALBUM BY GALT MACDERMOT
Hair The Original Soundtrack Recording
Hair: Original Soundtrack Recording is the soundtrack album from the 1979 musical film Hair. It was released on the RCA Victor label.

Wikipedia

Idiotype

In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T-cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region. The variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity-determining regions (CDRs) with unique amino acid sequences. They define the surface and properties of the variable region, determining the antigen specificity and therefore the idiotope of the molecule. Immunoglobulins or TCRs with a shared idiotope are the same idiotype. Antibody idiotype is determined by:

  • Gene rearrangement
  • Junctional diversity
  • P-nucleotides (palindromic nucleotides at sites of single-strand breaks)
  • N-nucleotides
  • Somatic hypermutations